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The Research and Educational Networking Association of Moldova (RENAM, http://www.renam.md) is a Public Association established to promote and support the development of national communicational and informational infrastructures, e-Infrastructure resources for the scientific and educational community (especially for research institutions, higher and secondary education, libraries and public collections, medical establishments), as well as to governmental organisations in Moldova. The principal purpose of RENAM’s activities consists in constant development of communication and computational infrastructure for research and education by means of collaborated efforts of scientific and educational institutions; providing access to the national and foreign computational infrastructures, scientific databases, open data repositories and educational informational content; permanent participation in extension of resources of the national e-Infrastructure; coordination and support of national distributed and HPC infrastructure development; integration of national computing resources to the regional and PanEuropean scientific computational infrastructures. RENAM coordinating MD-GRID NGI that at present is uniting all principal research and educational entities involved in support and development of National Computing infrastructure and applications. RENAM is the leading cloud compute and data infrastructure provider for the R&E community in Moldova. Since 2018 RENAM is coordinating the national initiative and related activities towards the realization of the European Open Science Cloud initiative in Moldova, providing computational resources of cloud infrastructure for supporting the generic and thematic services for open research data and ensuring open access to the national research data repositories.